News about DNA, genes and proteins

‘DNA replication in a tube’ provides new insights into chromatin assembly

Researchers from the Groth group (CPR) and the Mattiroli group (Hubrecht Institute) re-created DNA replication and chromatin assembly in a test tube. They discovered that the crosstalk between these two fundamental…

Bartender model predicts how drugs affect each person

A model based on numerous studies of people with type 2 diabetes can make a new type of prediction: how a certain drug would affect each person at the molecular biological level.

Bartender model predicts how drugs affect each person

A model based on numerous studies of people with type 2 diabetes can make a new type of prediction: how a certain drug would affect each person at the molecular biological level.

Exercise burns fat differently depending on the time of day

Physical activity at the right time of the day seems able to increase fat metabolism, at least in mice, shows a new study from Karolinska Institutet in Sweden and the University of Copenhagen.

A new publication from the Liu group in Nature Communications

"Mitotic DNA synthesis in response to replication stress requires the sequential action of DNA polymerases zeta and delta in human cells"

Alexander Hauser receives 4.8 mill DKK for peptide signalling systems project

Alexander Hauser has received the grant from Carlsberg Foundation’s Semper Ardens: Accelerate programme for the project “Discovery of Novel Peptide-GPCR Signalling Systems across Evolutionary Domains”.

Protein behavior in synthetic cells

Proteins may lose their normal function and lead to neurodegenerative diseases such as Alzheimer’s and Parkinson’s. This process, named protein aggregation, happens gradually in the brain over time, and it’s an…

Professor Ana Cvejic receives a grant to better understand the interplay between immune cells and cancer

Ana Cvejic, a professor at Biotech Research & Innovation Centre (BRIC), was awarded the DNRF Chair Grant of 10 million DKK over a period of three years to gain knowledge about the interaction of immune and tumor cells.

Four researchers from ILF receive 114 mill DKK to expand our knowledge of the human brain

Four ambitious research projects supported by the Lundbeck Foundation will give us completely new insights into the human brain, hopefully paving the way for new treatments of diseases such as Parkinson’s disease,…

A unique approach for studying changes in chemical markers on DNA

A new method to study specific changes in DNA which occur when cells divide addresses long-standing questions in molecular biology and opens new avenues in research into cancer, ageing and drug discovery

The proteins of Parkinson’s disease – a new project will give us a better understanding

Associate Professor Vito Foderà has received 2 mill DKK from Novo Nordisk Foundation for the project “Real-time Investigation of Protein Phase Separation and Amyloid Transition in Complex Environments”.

Now we understand better how cell division works. That puts us a step closer to devising more effective cancer therapies

How does a cell know when to divide? Researchers have found the answer, and it may prove significant to future cancer therapy.

Gene targeting in cell lines

Here we apply apply our expertise in CRISPR/Cas9-mediated genome editing to cell lines. We can now help you generating your new in vitro experimental system by knocking out your gene of interest, or introducing point…

Scientists finds stem cell network in ancient fish

An ancient fish called a ‘living fossil’ has helped researchers understand the basics of stem cells. This will further stem cell research and be a step in the direction of creating artificial organs

New gene technology is able to predict the effect of treatment on the individual breast cancer patient

How do you know whether breast cancer treatment will be able to cure the individual patient? New gene technology can tell us, and it may prove vital to patients.

Introducing Azadeh Shahsavar

Azadeh Shahsavar is a newly appointed Assistant Professor in the Department of Drug Design and Pharmacology.

CPR researchers on the prestigious Highly Cited Researchers list 2022

The "Highly Cited Researchers list" recognizes world-class researchers selected for their exceptional research performance, demonstrated by production of multiple highly cited papers (ranking in the top 1% by citations…

Fluorescent mouse blood will help us gain knowledge about brain diseases

A fluorescent protein makes it possible to follow disease progression in brain diseases such as Alzheimer’s, strokes, and depression. That may lead to better insight into diseases and possible new treatments.

Breakthrough in CRISPR may lead to more effective and safer gene editing

CRISPR has great potential within disease control due to its ability to modify our DNA. New research can prevent situations where CRISPR edits the wrong genes.

New insights into the growth of protein self-assembled structures

A study in Nature Communications Biology has identified a novel growth pathway for pathological protein aggregates. This discovery may give us a better understanding of Alzheimer’s and Parkinson’s.​​​​​​​

Excessive brain fluid can lead to risky surgery. New research seeks to change that

Researchers from the University of Copenhagen have discovered that fluid does not necessarily enter the brain the way one thought. According to one of the researchers behind the study, the result may lead to fewer major…

A new publication from the Hickson group in Molecular Cell

"RAD51 protects human cells from transcription-replication conflicts"

Warring genetic parasites could lead to new defenses against dangerous bacteria

Plasmids – a type of autonomous genetic parasites in bacteria – are armed with a previously unknown arsenal of CRISPR-Cas "gene tools" that are frequently deployed to combat other plasmids, according to research from th…

New DDSA Fellow will improve the predictions of protein variants using machine learning methods

Richard Michael is one of the first ten candidates to receive the prestigious PhD fellowship from the Danish Data Science Academy (DDSA). He will be conducting research within protein engineering at the Machine Learning…